Tax-loss harvesting alternatives for TGTX

Among the 28 Biotechnology peers screened, KRYS (Krystal Biotech) has tracked TGTX most closely over the past year, with a return correlation of 0.36. The strongest fund stand-in is XBI (SPDR S&P Biotech ETF) at 0.50 over the past year. Correlations are computed from daily closing-price returns aligned by trading day.

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STOCKS

Single-name peers

Ticker	Name	Sub-industry	1Y	3Y	5Y	10Y
KRYS	Krystal Biotech	Biotechnology	0.36	0.30	0.23	0.25
NBIX	Neurocrine Biosciences	Biotechnology	0.35	0.20	0.21	0.23
XNCR	Xencor Inc	Biotechnology	0.34	0.25	0.30	0.29
EXEL	Exelixis	Biotechnology	0.32	0.20	0.25	0.25
INCY	Incyte	Biotechnology	0.31	0.23	0.24	0.23
VCEL	Vericel	Biotechnology	0.29	0.22	0.38	0.28
REGN	Regeneron Pharmaceuticals	Biotechnology	0.28	0.18	0.16	0.20
HALO	Halozyme	Biotechnology	0.26	0.21	0.25	0.28
VIR	Vir Biotechnology, Inc.	Biotechnology	0.25	0.23	0.20	0.12
ROIV	Roivant Sciences	Biotechnology	0.24	0.28	0.24	—
ARWR	Arrowhead Pharmaceuticals	Biotechnology	0.24	0.28	0.38	0.29
PTGX	Protagonist Therapeutics, Inc.	Biotechnology	0.23	0.25	0.27	0.18
CYTK	Cytokinetics	Biotechnology	0.23	0.16	0.24	0.24
VRTX	Vertex Pharmaceuticals	Biotechnology	0.23	0.19	0.21	0.24
SRPT	Sarepta Therapeutics	Biotechnology	0.22	0.18	0.19	0.21
AMGN	Amgen Inc.	Biotechnology	0.22	0.19	0.14	0.21
FTRE	Fortrea	Biotechnology	0.21	0.09	0.07	—
RCUS	Arcus Biosciences, Inc.	Biotechnology	0.21	0.22	0.31	0.28
BMRN	BioMarin Pharmaceutical	Biotechnology	0.20	0.24	0.26	0.26
HRMY	Harmony Biosciences Holdings, Inc.	Biotechnology	0.20	0.24	0.27	0.24
BIIB	Biogen Inc.	Biotechnology	0.18	0.17	0.22	0.19
GILD	Gilead Sciences	Biotechnology	0.17	0.15	0.17	0.18
MRNA	Moderna Inc.	Biotechnology	0.17	0.17	0.17	0.16
RGEN	Repligen	Biotechnology	0.17	0.19	0.26	0.26
ALNY	Alnylam Pharmaceuticals	Biotechnology	0.14	0.17	0.24	0.23
LGND	Ligand Pharmaceuticals, Inc.	Biotechnology	0.14	0.21	0.30	0.30
ADMA	ADMA Biologics, Inc.	Biotechnology	0.11	0.22	0.34	0.22
UTHR	United Therapeutics	Biotechnology	0.04	0.15	0.13	0.17

ETFS

Fund stand-ins

An ETF is generally not 'substantially identical' to a single stock, which is why funds are the standard wash-sale-aware replacement.

Ticker	Name	Focus	Match	1Y	3Y	5Y	10Y
XBI	SPDR S&P Biotech ETF	Biotechnology (Equal Wt)	INDUSTRY	0.50	0.46	0.55	0.51
IBB	iShares Biotechnology ETF	Biotechnology	INDUSTRY	0.47	0.40	0.46	0.44
XPH	SPDR S&P Pharmaceuticals	Pharmaceuticals (Equal Wt)	INDUSTRY	0.47	0.37	0.42	0.42
IHE	iShares US Pharmaceuticals ETF	Pharmaceuticals	INDUSTRY	0.34	0.26	0.29	0.33
ARKG	ARK Genomic Revolution ETF	Genomics (Active)	INDUSTRY	0.34	0.35	0.47	0.45
VHT	Vanguard Health Care ETF	Health Care Sector	SECTOR	0.31	0.27	0.35	0.36
FHLC	Fidelity MSCI Health Care ETF	Health Care Sector	SECTOR	0.30	0.26	0.34	0.35
IYH	iShares US Healthcare ETF	Health Care Sector	SECTOR	0.28	0.24	0.31	0.33
XLV	Health Care Select Sector SPDR	Health Care Sector	SECTOR	0.25	0.22	0.28	0.30
PPH	VanEck Pharma ETF	Pharmaceuticals	INDUSTRY	0.22	0.20	0.24	0.29
IHF	iShares Health Care Providers	Health Care Providers	INDUSTRY	0.18	0.14	0.24	0.27
IHI	iShares Medical Devices ETF	Medical Devices	SUB-IND	0.12	0.18	0.33	0.34

NEXT STEPS

Harvesting a loss in TGTX?

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Replacement research for TGTX's peers

KRYS NBIX XNCR EXEL INCY VCEL REGN HALO VIR ROIV ARWR PTGX CYTK VRTX SRPT AMGN FTRE RCUS BMRN HRMY BIIB GILD MRNA RGEN ALNY LGND ADMA UTHR

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Method: Pearson correlation of daily closing-price returns, Yahoo Finance data, series aligned by trading day, refreshed weekly. A cell is blank when overlapping history covers less than 60% of its window. Correlation is descriptive, not predictive. Wash-sale treatment depends on facts and circumstances — confirm with a tax professional. Not investment advice.