Tax-loss harvesting alternatives for IBB

The closest fund alternative to IBB (Biotechnology) is XBI (SPDR S&P Biotech ETF), with a return correlation of 0.91 over the past year. Among single names in the fund's slice of the market, AMGN (Amgen Inc.) tracks it most closely at 0.62 over the past year. Correlations are computed from daily closing-price returns aligned by trading day.

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ETFS

Fund stand-ins

Funds covering similar ground. Two funds tracking the same index may themselves be 'substantially identical' for wash-sale purposes.

Ticker	Name	Focus	Match	1Y	3Y	5Y	10Y
XBI	SPDR S&P Biotech ETF	Biotechnology (Equal Wt)	INDUSTRY	0.91	0.91	0.90	0.91
VHT	Vanguard Health Care ETF	Health Care Sector	SECTOR	0.78	0.81	0.81	0.83
FHLC	Fidelity MSCI Health Care ETF	Health Care Sector	SECTOR	0.78	0.81	0.81	0.83
XPH	SPDR S&P Pharmaceuticals	Pharmaceuticals (Equal Wt)	INDUSTRY	0.77	0.80	0.81	0.82
IHE	iShares US Pharmaceuticals ETF	Pharmaceuticals	INDUSTRY	0.75	0.74	0.72	0.79
IYH	iShares US Healthcare ETF	Health Care Sector	SECTOR	0.75	0.78	0.78	0.80
ARKG	ARK Genomic Revolution ETF	Genomics (Active)	INDUSTRY	0.70	0.76	0.80	0.80
XLV	Health Care Select Sector SPDR	Health Care Sector	SECTOR	0.70	0.74	0.74	0.77
PPH	VanEck Pharma ETF	Pharmaceuticals	INDUSTRY	0.68	0.68	0.66	0.73
XHS	SPDR S&P Health Care Services	Health Care Services	INDUSTRY	0.42	0.56	0.66	0.66
IHI	iShares Medical Devices ETF	Medical Devices	SUB-IND	0.40	0.53	0.64	0.68
IHF	iShares Health Care Providers	Health Care Providers	INDUSTRY	0.28	0.38	0.48	0.57

STOCKS

Single-name peers

Single names inside the fund's slice of the market.

Ticker	Name	Sub-industry	1Y	3Y	5Y	10Y
AMGN	Amgen Inc.	Biotechnology	0.62	0.61	0.52	0.61
INCY	Incyte	Biotechnology	0.53	0.53	0.52	0.58
GILD	Gilead Sciences	Biotechnology	0.51	0.51	0.50	0.55
BMRN	BioMarin Pharmaceutical	Biotechnology	0.50	0.52	0.56	0.60
EXEL	Exelixis	Biotechnology	0.49	0.36	0.41	0.51
HALO	Halozyme	Biotechnology	0.48	0.47	0.49	0.54
BIIB	Biogen Inc.	Biotechnology	0.48	0.58	0.54	0.52
KRYS	Krystal Biotech	Biotechnology	0.47	0.50	0.40	0.40
ARWR	Arrowhead Pharmaceuticals	Biotechnology	0.42	0.53	0.60	0.49
CYTK	Cytokinetics	Biotechnology	0.40	0.38	0.42	0.43
ALNY	Alnylam Pharmaceuticals	Biotechnology	0.39	0.44	0.48	0.51
FTRE	Fortrea	Biotechnology	0.38	0.43	0.42	—
HRMY	Harmony Biosciences Holdings, Inc.	Biotechnology	0.35	0.32	0.37	—
ADMA	ADMA Biologics, Inc.	Biotechnology	0.31	0.38	0.44	0.33

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Replacement research for IBB's peers

AMGN INCY GILD BMRN EXEL HALO BIIB KRYS ARWR CYTK ALNY FTRE HRMY ADMA

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Method: Pearson correlation of daily closing-price returns, Yahoo Finance data, series aligned by trading day, refreshed weekly. A cell is blank when overlapping history covers less than 60% of its window. Correlation is descriptive, not predictive. Wash-sale treatment depends on facts and circumstances — confirm with a tax professional. Not investment advice.