Tax-loss harvesting alternatives for RCUS

Among the 28 Biotechnology peers screened, VIR (Vir Biotechnology, Inc.) has tracked RCUS most closely over the past year, with a return correlation of 0.49. The strongest fund stand-in is XBI (SPDR S&P Biotech ETF) at 0.57 over the past year. Correlations are computed from daily closing-price returns aligned by trading day.

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STOCKS

Single-name peers

Ticker	Name	Sub-industry	1Y	3Y	5Y	10Y
VIR	Vir Biotechnology, Inc.	Biotechnology	0.49	0.38	0.29	0.17
XNCR	Xencor Inc	Biotechnology	0.48	0.48	0.45	0.35
ARWR	Arrowhead Pharmaceuticals	Biotechnology	0.34	0.34	0.39	0.30
SRPT	Sarepta Therapeutics	Biotechnology	0.33	0.25	0.24	0.22
ROIV	Roivant Sciences	Biotechnology	0.31	0.35	0.27	—
NBIX	Neurocrine Biosciences	Biotechnology	0.29	0.26	0.25	0.25
CYTK	Cytokinetics	Biotechnology	0.25	0.24	0.28	0.24
GILD	Gilead Sciences	Biotechnology	0.23	0.23	0.24	0.21
REGN	Regeneron Pharmaceuticals	Biotechnology	0.23	0.29	0.24	0.25
ADMA	ADMA Biologics, Inc.	Biotechnology	0.23	0.31	0.34	0.22
VRTX	Vertex Pharmaceuticals	Biotechnology	0.22	0.22	0.22	0.24
TGTX	TG Therapeutics, Inc.	Biotechnology	0.21	0.22	0.31	0.28
FTRE	Fortrea	Biotechnology	0.21	0.25	0.23	—
LGND	Ligand Pharmaceuticals, Inc.	Biotechnology	0.21	0.29	0.34	0.29
INCY	Incyte	Biotechnology	0.20	0.27	0.27	0.29
PTGX	Protagonist Therapeutics, Inc.	Biotechnology	0.20	0.28	0.22	0.15
AMGN	Amgen Inc.	Biotechnology	0.19	0.22	0.20	0.23
KRYS	Krystal Biotech	Biotechnology	0.19	0.32	0.25	0.23
HRMY	Harmony Biosciences Holdings, Inc.	Biotechnology	0.18	0.20	0.25	—
HALO	Halozyme	Biotechnology	0.17	0.21	0.23	0.27
EXEL	Exelixis	Biotechnology	0.16	0.19	0.24	0.26
RGEN	Repligen	Biotechnology	0.14	0.23	0.27	0.27
UTHR	United Therapeutics	Biotechnology	0.14	0.17	0.13	0.17
MRNA	Moderna Inc.	Biotechnology	0.13	0.18	0.19	0.17
BMRN	BioMarin Pharmaceutical	Biotechnology	0.13	0.27	0.30	0.28
VCEL	Vericel	Biotechnology	0.13	0.28	0.35	0.27
ALNY	Alnylam Pharmaceuticals	Biotechnology	0.07	0.17	0.23	0.24
BIIB	Biogen Inc.	Biotechnology	0.03	0.23	0.25	0.20

ETFS

Fund stand-ins

An ETF is generally not 'substantially identical' to a single stock, which is why funds are the standard wash-sale-aware replacement.

Ticker	Name	Focus	Match	1Y	3Y	5Y	10Y
XBI	SPDR S&P Biotech ETF	Biotechnology (Equal Wt)	INDUSTRY	0.57	0.59	0.59	0.51
IBB	iShares Biotechnology ETF	Biotechnology	INDUSTRY	0.48	0.53	0.52	0.46
XPH	SPDR S&P Pharmaceuticals	Pharmaceuticals (Equal Wt)	INDUSTRY	0.48	0.50	0.48	0.41
ARKG	ARK Genomic Revolution ETF	Genomics (Active)	INDUSTRY	0.38	0.46	0.48	0.44
IHE	iShares US Pharmaceuticals ETF	Pharmaceuticals	INDUSTRY	0.29	0.37	0.36	0.34
VHT	Vanguard Health Care ETF	Health Care Sector	SECTOR	0.23	0.37	0.39	0.37
FHLC	Fidelity MSCI Health Care ETF	Health Care Sector	SECTOR	0.23	0.36	0.38	0.37
PPH	VanEck Pharma ETF	Pharmaceuticals	INDUSTRY	0.19	0.29	0.29	0.30
IYH	iShares US Healthcare ETF	Health Care Sector	SECTOR	0.19	0.34	0.35	0.35
XLV	Health Care Select Sector SPDR	Health Care Sector	SECTOR	0.16	0.31	0.33	0.33
IHI	iShares Medical Devices ETF	Medical Devices	SUB-IND	0.04	0.21	0.29	0.30
IHF	iShares Health Care Providers	Health Care Providers	INDUSTRY	0.03	0.16	0.23	0.28

NEXT STEPS

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Replacement research for RCUS's peers

VIR XNCR ARWR SRPT ROIV NBIX CYTK GILD REGN ADMA VRTX TGTX FTRE LGND INCY PTGX AMGN KRYS HRMY HALO EXEL RGEN UTHR MRNA BMRN VCEL ALNY BIIB

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Method: Pearson correlation of daily closing-price returns, Yahoo Finance data, series aligned by trading day, refreshed weekly. A cell is blank when overlapping history covers less than 60% of its window. Correlation is descriptive, not predictive. Wash-sale treatment depends on facts and circumstances — confirm with a tax professional. Not investment advice.