Tax-loss harvesting alternatives for PTCT

Among the 30 Pharmaceuticals peers screened, ALKS (Alkermes plc) has tracked PTCT most closely over the past year, with a return correlation of 0.32. The strongest fund stand-in is XBI (SPDR S&P Biotech ETF) at 0.58 over the past year. Correlations are computed from daily closing-price returns aligned by trading day.

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STOCKS

Single-name peers

Ticker	Name	Sub-industry	1Y	3Y	5Y	10Y
ALKS	Alkermes plc	Pharmaceuticals	0.32	0.26	0.27	0.22
ACAD	Acadia Pharmaceuticals	Pharmaceuticals	0.31	0.28	0.28	0.22
NVO	Novo Nordisk	Pharmaceuticals	0.26	0.11	0.11	0.13
LQDA	Liquidia Corporation	Pharmaceuticals	0.25	0.16	0.16	0.16
INDV	Indivior	Pharmaceuticals	0.25	0.19	0.04	0.03
LLY	Eli Lilly	Pharmaceuticals	0.25	0.19	0.16	0.16
JAZZ	Jazz Pharmaceuticals	Pharmaceuticals	0.23	0.20	0.24	0.23
GSK	GSK plc	Pharmaceuticals	0.22	0.14	0.13	0.15
AZN	AstraZeneca	Pharmaceuticals	0.20	0.18	0.18	0.18
CORT	Corcept Therapeutics Incorporated	Pharmaceuticals	0.19	0.11	0.15	0.16
INVA	Innoviva, Inc.	Pharmaceuticals	0.19	0.20	0.19	0.21
MRK	Merck & Co.	Pharmaceuticals	0.19	0.15	0.14	0.15
AMRX	Amneal Pharmaceuticals	Pharmaceuticals	0.18	0.19	0.16	0.21
BMY	Bristol-Myers Squibb	Pharmaceuticals	0.17	0.15	0.14	0.17
PFE	Pfizer Inc.	Pharmaceuticals	0.14	0.15	0.12	0.14
COLL	Collegium Pharmaceutical, Inc.	Pharmaceuticals	0.12	0.15	0.19	0.17
JNJ	Johnson & Johnson	Pharmaceuticals	0.12	0.13	0.12	0.12
ABBV	AbbVie Inc.	Pharmaceuticals	0.12	0.14	0.14	0.18
SUPN	Supernus Pharmaceuticals, Inc.	Pharmaceuticals	0.11	0.14	0.20	0.21
ANIP	ANI Pharmaceuticals, Inc.	Pharmaceuticals	0.10	0.19	0.20	0.24
PCRX	Pacira BioSciences, Inc.	Pharmaceuticals	0.10	0.12	0.17	0.16
ELAN	Elanco	Pharmaceuticals	0.09	0.15	0.18	0.22
ZTS	Zoetis Inc.	Pharmaceuticals	0.08	0.18	0.21	0.22
SNY	Sanofi S.A.	Pharmaceuticals	0.08	0.16	0.16	0.16
PAHC	Phibro Animal Health	Pharmaceuticals	0.08	0.20	0.20	0.18
OGN	Organon & Co.	Pharmaceuticals	0.06	0.14	0.16	—
VTRS	Viatris	Pharmaceuticals	0.06	0.17	0.18	0.15
PBH	Prestige Consumer Healthcare	Pharmaceuticals	0.04	0.15	0.14	0.15
PRGO	Perrigo	Pharmaceuticals	0.02	0.18	0.17	0.15
AMPH	Amphstar Pharmaceuticals, Inc.	Pharmaceuticals	-0.04	0.09	0.10	0.16

ETFS

Fund stand-ins

An ETF is generally not 'substantially identical' to a single stock, which is why funds are the standard wash-sale-aware replacement.

Ticker	Name	Focus	Match	1Y	3Y	5Y	10Y
XBI	SPDR S&P Biotech ETF	Biotechnology (Equal Wt)	INDUSTRY	0.58	0.51	0.54	0.47
IBB	iShares Biotechnology ETF	Biotechnology	INDUSTRY	0.54	0.46	0.48	0.42
XPH	SPDR S&P Pharmaceuticals	Pharmaceuticals (Equal Wt)	INDUSTRY	0.41	0.39	0.43	0.39
VHT	Vanguard Health Care ETF	Health Care Sector	SECTOR	0.38	0.34	0.36	0.34
FHLC	Fidelity MSCI Health Care ETF	Health Care Sector	SECTOR	0.38	0.34	0.35	0.33
IHE	iShares US Pharmaceuticals ETF	Pharmaceuticals	INDUSTRY	0.36	0.33	0.33	0.34
IYH	iShares US Healthcare ETF	Health Care Sector	SECTOR	0.34	0.31	0.32	0.31
XLV	Health Care Select Sector SPDR	Health Care Sector	SECTOR	0.31	0.30	0.30	0.29
PPH	VanEck Pharma ETF	Pharmaceuticals	INDUSTRY	0.31	0.26	0.27	0.28
XHE	SPDR S&P Health Care Equipment	Medical Devices (Equal Wt)	SUB-IND	0.24	0.32	0.37	0.34
IHF	iShares Health Care Providers	Health Care Providers	INDUSTRY	0.24	0.15	0.21	0.25
IHI	iShares Medical Devices ETF	Medical Devices	SUB-IND	0.18	0.26	0.29	0.29

NEXT STEPS

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Replacement research for PTCT's peers

ALKS ACAD NVO LQDA INDV LLY JAZZ GSK AZN CORT INVA MRK AMRX BMY PFE COLL JNJ ABBV SUPN ANIP PCRX ELAN ZTS SNY PAHC OGN VTRS PBH PRGO AMPH

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Method: Pearson correlation of daily closing-price returns, Yahoo Finance data, series aligned by trading day, refreshed weekly. A cell is blank when overlapping history covers less than 60% of its window. Correlation is descriptive, not predictive. Wash-sale treatment depends on facts and circumstances — confirm with a tax professional. Not investment advice.